As of 2025-09-18, the EV/EBITDA ratio of Epizyme Inc (EPZM) is -2.14. EV/EBITDA ratio is calculated by dividing the enterprise value by the TTM EBITDA. EPZM's latest enterprise value is 409.28 mil USD. EPZM's TTM EBITDA according to its financial statements is -191.16 mil USD. Dividing these 2 quantities gives us the above EPZM EV/EBITDA ratio.
Note: valuation result may not be accurate due to the company's negative EBITDA.
| Range | Selected | |
| Trailing P/E multiples | 11.5x - 14.5x | 13.6x |
| Forward P/E multiples | 16.4x - 34.0x | 19.2x |
| Fair Price | (19.63) - (17.45) | (19.59) |
| Upside | -1435.5% - -1287.1% | -1432.4% |
| Date | EV/EBITDA |