As of 2025-09-16, the EV/EBITDA ratio of Ionis Pharmaceuticals Inc (IONS) is -33.93. EV/EBITDA ratio is calculated by dividing the enterprise value by the TTM EBITDA. IONS's latest enterprise value is 10,697.04 mil USD. IONS's TTM EBITDA according to its financial statements is -315.31 mil USD. Dividing these 2 quantities gives us the above IONS EV/EBITDA ratio.
Note: valuation result may not be accurate due to the company's negative EBITDA.
| Range | Selected | |
| Trailing P/E multiples | 9.6x - 12.0x | 10.2x |
| Forward P/E multiples | 9.0x - 9.7x | 9.3x |
| Fair Price | (25.08) - (25.20) | (25.30) |
| Upside | -141.1% - -141.2% | -141.4% |
| Date | EV/EBITDA |
| 2025-09-12 | -34.97 |
| 2025-09-11 | -35.41 |
| 2025-09-10 | -35.39 |
| 2025-09-09 | -35.59 |
| 2025-09-08 | -33.88 |
| 2025-09-05 | -33.99 |
| 2025-09-04 | -33.04 |
| 2025-09-03 | -33.62 |
| 2025-09-02 | -32.10 |
| 2025-08-29 | -24.59 |
| 2025-08-28 | -24.58 |
| 2025-08-27 | -24.65 |
| 2025-08-26 | -24.36 |
| 2025-08-25 | -24.18 |
| 2025-08-22 | -24.62 |
| 2025-08-21 | -24.89 |
| 2025-08-20 | -24.68 |
| 2025-08-19 | -24.51 |
| 2025-08-18 | -24.99 |
| 2025-08-15 | -25.17 |
| 2025-08-14 | -24.70 |
| 2025-08-13 | -24.83 |
| 2025-08-12 | -23.97 |
| 2025-08-11 | -23.68 |
| 2025-08-08 | -24.09 |
| 2025-08-07 | -23.79 |
| 2025-08-06 | -23.61 |
| 2025-08-05 | -24.80 |
| 2025-08-04 | -25.00 |
| 2025-08-01 | -24.79 |
| 2025-07-31 | -24.77 |
| 2025-07-30 | -24.96 |
| 2025-07-29 | -24.01 |
| 2025-07-28 | -23.85 |
| 2025-07-25 | -24.39 |
| 2025-07-24 | -24.35 |
| 2025-07-23 | -24.46 |
| 2025-07-22 | -24.25 |
| 2025-07-21 | -24.04 |
| 2025-07-18 | -24.15 |
| 2025-07-17 | -24.36 |
| 2025-07-16 | -24.66 |
| 2025-07-15 | -24.27 |
| 2025-07-14 | -24.55 |
| 2025-07-11 | -24.13 |
| 2025-07-10 | -24.46 |
| 2025-07-09 | -24.69 |
| 2025-07-08 | -23.94 |
| 2025-07-07 | -24.16 |
| 2025-07-03 | -24.78 |