As of 2025-12-16, the Relative Valuation of Ionis Pharmaceuticals Inc (IONS) is (20.10) USD. This relative valuation is based on P/E multiples. With the latest stock price at 79.76 USD, the upside of Ionis Pharmaceuticals Inc based on Relative Valuation is -125.2%.
The range of the Relative Valuation is (16.24) - (20.92) USD.
Note: valuation result may not be accurate due to the company's negative earnings.
| Range | Selected | |
| Trailing P/E multiples | 10.1x - 13.2x | 12.5x |
| Forward P/E multiples | 10.3x - 13.3x | 12.9x |
| Fair Price | (16.24) - (20.92) | (20.10) |
| Upside | -120.4% - -126.2% | -125.2% |
| Date | P/E |
| 2025-12-15 | -50.40 |
| 2025-12-12 | -51.07 |
| 2025-12-11 | -50.00 |
| 2025-12-10 | -49.68 |
| 2025-12-09 | -49.83 |
| 2025-12-08 | -51.50 |
| 2025-12-05 | -51.61 |
| 2025-12-04 | -51.69 |
| 2025-12-03 | -51.71 |
| 2025-12-02 | -51.38 |
| 2025-12-01 | -51.81 |
| 2025-11-28 | -52.27 |
| 2025-11-26 | -52.25 |
| 2025-11-25 | -51.14 |
| 2025-11-24 | -49.61 |
| 2025-11-21 | -48.08 |
| 2025-11-20 | -46.20 |
| 2025-11-19 | -46.76 |
| 2025-11-18 | -47.07 |
| 2025-11-17 | -46.29 |
| 2025-11-14 | -45.21 |
| 2025-11-13 | -44.13 |
| 2025-11-12 | -45.92 |
| 2025-11-11 | -45.78 |
| 2025-11-10 | -43.94 |
| 2025-11-07 | -46.47 |
| 2025-11-06 | -46.82 |
| 2025-11-05 | -47.19 |
| 2025-11-04 | -46.05 |
| 2025-11-03 | -46.54 |
| 2025-10-31 | -46.95 |
| 2025-10-30 | -46.86 |
| 2025-10-29 | -45.42 |
| 2025-10-28 | -46.49 |
| 2025-10-27 | -46.12 |
| 2025-10-24 | -44.77 |
| 2025-10-23 | -45.18 |
| 2025-10-22 | -45.18 |
| 2025-10-21 | -45.27 |
| 2025-10-20 | -46.47 |
| 2025-10-17 | -46.18 |
| 2025-10-16 | -46.17 |
| 2025-10-15 | -45.74 |
| 2025-10-14 | -45.10 |
| 2025-10-13 | -44.60 |
| 2025-10-10 | -44.21 |
| 2025-10-09 | -44.40 |
| 2025-10-08 | -44.20 |
| 2025-10-07 | -43.56 |
| 2025-10-06 | -43.61 |