As of 2026-08-15, the Relative Valuation of Spero Therapeutics Inc (SPRO) is 3.00 USD. This relative valuation is based on P/E multiples. With the latest stock price at 1.24 USD, the upside of Spero Therapeutics Inc based on Relative Valuation is 141.9%.
The range of the Relative Valuation is 0.04 - 6.46 USD.
| Range | Selected | |
| Trailing P/E multiples | 20.8x - 24.5x | 22.6x |
| Forward P/E multiples | 26.8x - 29.6x | 28.2x |
| Fair Price | 0.04 - 6.46 | 3.00 |
| Upside | -97.1% - 420.7% | 141.9% |
| Date | P/E |
| 2026-08-06 | 4.83 |
| 2026-08-05 | 4.79 |
| 2026-08-04 | 4.67 |
| 2026-08-03 | 4.37 |
| 2026-07-31 | 4.45 |
| 2026-07-30 | 4.56 |
| 2026-07-29 | 4.52 |
| 2026-07-28 | 4.54 |
| 2026-07-27 | 4.48 |
| 2026-07-24 | 4.52 |
| 2026-07-23 | 4.41 |
| 2026-07-22 | 4.83 |
| 2026-07-21 | 5.24 |
| 2026-07-20 | 5.47 |
| 2026-07-17 | 6.00 |
| 2026-07-16 | 5.97 |
| 2026-07-15 | 6.46 |
| 2026-07-14 | 6.46 |
| 2026-07-13 | 8.29 |
| 2026-07-10 | 7.98 |
| 2026-07-09 | 8.06 |
| 2026-07-08 | 8.25 |
| 2026-07-07 | 8.21 |
| 2026-07-06 | 8.32 |
| 2026-07-02 | 8.36 |
| 2026-07-01 | 8.44 |
| 2026-06-30 | 8.40 |
| 2026-06-29 | 8.59 |
| 2026-06-26 | 8.59 |
| 2026-06-25 | 7.68 |
| 2026-06-24 | 7.98 |
| 2026-06-23 | 8.17 |
| 2026-06-22 | 8.40 |
| 2026-06-18 | 8.67 |
| 2026-06-17 | 8.02 |
| 2026-06-16 | 10.53 |
| 2026-06-15 | 11.06 |
| 2026-06-12 | 10.83 |
| 2026-06-11 | 10.26 |
| 2026-06-10 | 9.65 |
| 2026-06-09 | 9.77 |
| 2026-06-08 | 10.41 |
| 2026-06-05 | 10.72 |
| 2026-06-04 | 11.33 |
| 2026-06-03 | 10.64 |
| 2026-06-02 | 10.76 |
| 2026-06-01 | 10.76 |
| 2026-05-29 | 10.76 |
| 2026-05-28 | 11.02 |
| 2026-05-27 | 11.14 |