As of 2025-07-07, the Relative Valuation of Spero Therapeutics Inc (SPRO) is (26.98) USD. This relative valuation is based on P/E multiples. With the latest stock price at 2.91 USD, the upside of Spero Therapeutics Inc based on Relative Valuation is -1027.3%.
The range of the Relative Valuation is (21.84) - (30.22) USD.
Note: valuation result may not be accurate due to the company's negative earnings.
| Range | Selected | |
| Trailing P/E multiples | 15.9x - 24.2x | 20.0x |
| Forward P/E multiples | 17.5x - 28.9x | 23.2x |
| Fair Price | (21.84) - (30.22) | (26.98) |
| Upside | -850.4% - -1138.5% | -1027.3% |
| Date | P/E |
| 2025-07-03 | -2.33 |
| 2025-07-02 | -2.32 |
| 2025-07-01 | -2.32 |
| 2025-06-30 | -2.32 |
| 2025-06-27 | -2.36 |
| 2025-06-26 | -2.32 |
| 2025-06-25 | -2.32 |
| 2025-06-24 | -2.31 |
| 2025-06-23 | -2.35 |
| 2025-06-20 | -2.42 |
| 2025-06-18 | -2.36 |
| 2025-06-17 | -2.32 |
| 2025-06-16 | -2.28 |
| 2025-06-13 | -2.27 |
| 2025-06-12 | -2.32 |
| 2025-06-11 | -2.24 |
| 2025-06-10 | -2.28 |
| 2025-06-09 | -2.21 |
| 2025-06-06 | -2.00 |
| 2025-06-05 | -2.05 |
| 2025-06-04 | -2.13 |
| 2025-06-03 | -2.12 |
| 2025-06-02 | -2.20 |
| 2025-05-30 | -2.00 |
| 2025-05-29 | -1.71 |
| 2025-05-28 | -1.88 |
| 2025-05-27 | -0.55 |
| 2025-05-23 | -0.56 |
| 2025-05-22 | -0.56 |
| 2025-05-21 | -0.55 |
| 2025-05-20 | -0.55 |
| 2025-05-19 | -0.55 |
| 2025-05-16 | -0.52 |
| 2025-05-15 | -0.52 |
| 2025-05-14 | -0.52 |
| 2025-05-13 | -0.55 |
| 2025-05-12 | -0.49 |
| 2025-05-09 | -0.50 |
| 2025-05-08 | -0.46 |
| 2025-05-07 | -0.46 |
| 2025-05-06 | -0.47 |
| 2025-05-05 | -0.49 |
| 2025-05-02 | -0.52 |
| 2025-05-01 | -0.53 |
| 2025-04-30 | -0.53 |
| 2025-04-29 | -0.54 |
| 2025-04-28 | -0.57 |
| 2025-04-25 | -0.58 |
| 2025-04-24 | -0.58 |
| 2025-04-23 | -0.58 |