As of 2026-09-13, the Relative Valuation of Spero Therapeutics Inc (SPRO) is 1.51 USD. This relative valuation is based on P/E multiples. With the latest stock price at 1.13 USD, the upside of Spero Therapeutics Inc based on Relative Valuation is 33.3%.
The range of the Relative Valuation is 0.04 - 3.30 USD.
| Range | Selected | |
| Trailing P/E multiples | 21.5x - 25.9x | 23.3x |
| Forward P/E multiples | 27.6x - 44.6x | 30.4x |
| Fair Price | 0.04 - 3.30 | 1.51 |
| Upside | -96.7% - 191.8% | 33.3% |
| Date | P/E |
| 2026-09-04 | 9.41 |
| 2026-09-03 | 9.57 |
| 2026-09-02 | 9.57 |
| 2026-09-01 | 9.41 |
| 2026-08-31 | 9.57 |
| 2026-08-28 | 9.41 |
| 2026-08-27 | 9.49 |
| 2026-08-26 | 9.57 |
| 2026-08-25 | 9.65 |
| 2026-08-24 | 9.53 |
| 2026-08-21 | 9.57 |
| 2026-08-20 | 9.49 |
| 2026-08-19 | 9.65 |
| 2026-08-18 | 9.41 |
| 2026-08-17 | 9.33 |
| 2026-08-14 | 9.65 |
| 2026-08-13 | 9.72 |
| 2026-08-12 | 9.33 |
| 2026-08-11 | 9.65 |
| 2026-08-10 | 9.65 |
| 2026-08-07 | 9.88 |
| 2026-08-06 | 9.96 |
| 2026-08-05 | 9.88 |
| 2026-08-04 | 9.65 |
| 2026-08-03 | 9.02 |
| 2026-07-31 | 9.18 |
| 2026-07-30 | 9.41 |
| 2026-07-29 | 9.33 |
| 2026-07-28 | 9.37 |
| 2026-07-27 | 9.25 |
| 2026-07-24 | 9.33 |
| 2026-07-23 | 9.10 |
| 2026-07-22 | 9.96 |
| 2026-07-21 | 10.82 |
| 2026-07-20 | 11.29 |
| 2026-07-17 | 12.39 |
| 2026-07-16 | 12.31 |
| 2026-07-15 | 13.33 |
| 2026-07-14 | 13.33 |
| 2026-07-13 | 17.10 |
| 2026-07-10 | 16.47 |
| 2026-07-09 | 16.63 |
| 2026-07-08 | 17.02 |
| 2026-07-07 | 16.94 |
| 2026-07-06 | 17.17 |
| 2026-07-02 | 17.25 |
| 2026-07-01 | 17.41 |
| 2026-06-30 | 17.33 |
| 2026-06-29 | 17.72 |
| 2026-06-26 | 17.72 |