As of 2025-12-16, the EV/EBITDA ratio of OPKO Health Inc (OPK) is -13.59. EV/EBITDA ratio is calculated by dividing the enterprise value by the TTM EBITDA. OPK's latest enterprise value is 970.24 mil USD. OPK's TTM EBITDA according to its financial statements is -71.40 mil USD. Dividing these 2 quantities gives us the above OPK EV/EBITDA ratio.
| Range | Selected | |
| Trailing P/E multiples | 12.4x - 14.0x | 13.2x |
| Forward P/E multiples | 13.3x - 15.6x | 14.7x |
| Fair Price | (1.07) - 1.94 | 0.35 |
| Upside | -179.3% - 43.8% | -74.4% |
| Date | EV/EBITDA |
| 2025-12-15 | -13.59 |
| 2025-12-12 | -13.91 |
| 2025-12-11 | -14.02 |
| 2025-12-10 | -13.80 |
| 2025-12-09 | -13.70 |
| 2025-12-08 | -13.27 |
| 2025-12-05 | -13.48 |
| 2025-12-04 | -13.59 |
| 2025-12-03 | -13.80 |
| 2025-12-02 | -13.37 |
| 2025-12-01 | -13.27 |
| 2025-11-28 | -13.70 |
| 2025-11-26 | -13.48 |
| 2025-11-25 | -13.59 |
| 2025-11-24 | -13.05 |
| 2025-11-21 | -13.27 |
| 2025-11-20 | -13.05 |
| 2025-11-19 | -13.16 |
| 2025-11-18 | -12.84 |
| 2025-11-17 | -12.73 |
| 2025-11-14 | -12.84 |
| 2025-11-13 | -12.84 |
| 2025-11-12 | -13.27 |
| 2025-11-11 | -13.37 |
| 2025-11-10 | -13.37 |
| 2025-11-07 | -13.48 |
| 2025-11-06 | -13.91 |
| 2025-11-05 | -13.48 |
| 2025-11-04 | -14.02 |
| 2025-11-03 | -14.13 |
| 2025-10-31 | -13.70 |
| 2025-10-30 | -14.77 |
| 2025-10-29 | -14.45 |
| 2025-10-28 | -14.56 |
| 2025-10-27 | -14.66 |
| 2025-10-24 | -15.20 |
| 2025-10-23 | -15.42 |
| 2025-10-22 | -15.31 |
| 2025-10-21 | -14.99 |
| 2025-10-20 | -15.52 |
| 2025-10-17 | -15.42 |
| 2025-10-16 | -15.20 |
| 2025-10-15 | -15.42 |
| 2025-10-14 | -15.42 |
| 2025-10-13 | -15.31 |
| 2025-10-10 | -15.31 |
| 2025-10-09 | -15.85 |
| 2025-10-08 | -15.74 |
| 2025-10-07 | -15.63 |
| 2025-10-06 | -16.06 |